AP01172PU-N ACVRL1 / ALK1 Antikörper

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0.1 mg / 370,00 €
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

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Rabbit anti Human, Mouse, Rat ACVRL1 / ALK1

AP01172PU-N

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  • AP01172PU-N

Produktbeschreibung für ACVRL1 / ALK1

Rabbit anti Human, Mouse, Rat ACVRL1 / ALK1.
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay, Immunocytochemistry/Immunofluorescence, Western blot / Immunoblot, Paraffin Sections.

Produktdaten von ACVRL1 / ALK1

Produkt-Kategorie Primärantikörper
Target-Kategorie
Menge 0.1 mg
Synonyme ACVRLK1, Activin A receptor type II-like 1, Activin receptor-like kinase 1, SKR3, Serine/threonine-protein kinase receptor R3, TGF-B superfamily receptor type I
Präsentation Aff - Purified
Reaktivität Hu, Ms, Rt
Anwendungen E, ICC/IF, P, WB
Klonalität Polyclonal
Wirt Rabbit
Molecular weight ~56 kDa
Shipping to Worldwide
PDF datasheet Datenblatt ansehen
Hersteller OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datenblatt-Auszug

Immunogen
Swiss Prot Num:
P37023
Immunogen:
Synthetic peptide corresponding to amino acids 200-250 of Human ACVRL1.
GeneID:
94
Anwendung Western Blot: 1/500-1/1000.
Immunofluorescence: 1/50-1/200.
Immunohistochemistry on Paraffin Sections: 1/50-1/200.
Background Mutations in two genes, Endoglin (also designated CD105) and ACVRL1 / ALK1 (activin receptorlike kinase 1, also designated TGFβ superfamily RI), are responsible for HHT. Endoglin is mutated in HHT1, and ALK-1 is mutated in HHT2, both of which are thought to be caused by haploinsufficiency. Endoglin and ALK-1 are type III and type I members of the TGFβ receptor superfamily, respectively, that are expressed on vascular endothelial cells. Endoglin can only bind ligands of the TGFβ superfamily via association with the respective ligand binding receptors for TGFβ1, TGFβ3, Activin-A, BMP-2 and BMP-7.
ALK-1 preferentially binds TGFβ1 and is expressed in bone marrow stromal cells, lung, brain, kidney and spleen.
Concentration 1.0 mg/ml
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: One year from despatch
Format
Purification:
Affinity Chromatography using epitope-specific immunogen
Buffer System:
Phosphate buffered saline (PBS), pH 7.2
Preservatives:
0.05% Sodium Azide
State:
Liquid purified Ig fraction (> 95% pure by SDS-PAGE)
Aff - Purified
Species Reactivity
Species reactivity (expected):
Mouse and Rat.
Species reactivity (tested):
Human.
Specificity
Specificity:
This antibody detects endogenous levels of ALK-1 protein (region surrounding Phe231).
Gene ID 94

Accessory Products

Proteins and/or Positive Controls

Proteine zu ACVRL1 / ALK1 (9 Produkte)

Katalog-Nr. Spezies Präs. Reinheit   Source  

ACVRL1 / ALK1 (transcript variant 2)

ACVRL1 / ALK1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / 748,00 €
  OriGene Technologies, Inc.

ACVRL1 / ALK1 (22-118, His-tag)

ACVRL1 / ALK1 Human Purified > 95 % by SDS - PAGE Insect cells
0.25 mg / 1.070,00 €
  OriGene Technologies GmbH

ACVRL1 / ALK1 (22-118, His-tag)

ACVRL1 / ALK1 Human Purified > 95 % by SDS - PAGE Insect cells
50 µg / 320,00 €
  OriGene Technologies GmbH

ACVRL1 / ALK1

ACVRL1 / ALK1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

ACVRL1 / ALK1

ACVRL1 / ALK1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

ACVRL1 / ALK1

ACVRL1 / ALK1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

ACVRL1 / ALK1

ACVRL1 / ALK1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

ACVRL1 / ALK1

ACVRL1 / ALK1 Human
  Abnova Taiwan Corp.

ACVRL1 / ALK1

ACVRL1 / ALK1 Human
  Abnova Taiwan Corp.

Positive controls for ACVRL1 / ALK1 (4 Produkte)

Katalog-Nr. Spezies Präs. Reinheit   Source  

Activin A Receptor Type II-like 1 Lysate

Western Blot: Activin Receptor Type 2-like 1 Lysate [NBL1-07298] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for ACVRL1 Protein
  Novus Biologicals Inc.

Activin A Receptor Type II-like 1 Lysate

Western Blot: Activin Receptor Type 2-like 1 Lysate [NBL1-07299] - Western Blot experiments.  Left-Control; Right -Over-expression Lysate for Activin Receptor Type 2-like 1_x000d_ Protein
  Novus Biologicals Inc.

ACVRL1 overexpression lysate

ACVRL1 overexpression lysate
  OriGene Technologies, Inc.

ACVRL1 overexpression lysate

ACVRL1 overexpression lysate
0.1 mg / 495,00 €
  OriGene Technologies, Inc.
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