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AP21636PU-N Bovine Spongiform Encephalopathy / BSE (162-170) Antikörper

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Rabbit anti Birds, Bovine, Sheep Bovine Spongiform Encephalopathy / BSE

Produktbeschreibung für Bovine Spongiform Encephalopathy / BSE

Rabbit anti Birds, Bovine, Sheep Bovine Spongiform Encephalopathy / BSE.
Properties: (162-170)
Presentation: Purified
Product is tested for Western blot / Immunoblot.

Produktdaten von Bovine Spongiform Encephalopathy / BSE

Produkt-Kategorie Primärantikörper
Menge 0.1 mg
Präsentation Purified
Reaktivität Av, Bov, Sh
Anwendungen WB
Klonalität Polyclonal
Wirt Rabbit
Shipping to Worldwide
PDF datasheet Datenblatt ansehen
Hersteller Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datenblatt-Auszug

Immunogen
Immunogen:
Amino acids 162-170 of BSE protein
Eigenschaften 162-170
Anwendung Western blot: 0.5 - 2 µg/ml.
Recommended Positive Control: Recombinant fusion protein
Background BSE, also known as prion protein, is a membrane glycosylphosphatidylinositol-anchored glycoprotein belonging to the prion family of proteins and is responsible for several transmissible neurodegenerative spongiform encephalopathies. Though the exact function of BSE is not clear, reports suggest that it has a tendency to aggregate forming polymers known as rods and might act as a signaling neurotransmitter. BSE acts as a potent anti-apoptotic protein against BAX-mediated cell-death. Expression is higher in the brain of humans and animals infected with several degenerative neurological diseases such as kuru, Creutzfeldt-Jakob disease (CJD), Gerstmann-Straussler syndrome (GSS), scrapie, bovine spongiform encephalopathy (BSE), and transmissible mink encephalopathy (TME). Aberration in this protein is also associated with fatal familial insomnia and Huntington disease-like 1.
Concentration 0,5 mg/ml
General Readings
  1. Korth C, Stierli B, Streit P, Moser M, Schaller O, Fischer R, et al. Prion (PrPSc)-specific epitope defined by a monoclonal antibody. Nature. 1997 Nov 6;390(6655):74-7. PubMed PMID: 9363892.
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Protein G Chromatography
Buffer System:
PBS containing 0.2% gelatin and 0.05% sodium azide
State:
Liquid purified Ig fraction
Purified
Specificity
Specificity:
This antibody reacts to Bovine Spongiform Encephalopathy (BSE).
Species:
Sheep, Cow, Avian.

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