AM08111FC-N CD5 Antikörper

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0.5 mg / 450,00 €
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Kurzübersicht

Mouse anti Feline CD5 f43

AM08111FC-N

Produktbeschreibung für CD5

Mouse anti Feline CD5 f43.
Presentation: FITC
Product is tested for Flow Cytometry.

Produktdaten von CD5

Produkt-Kategorie Primärantikörper
Menge 0.5 mg
Synonyme LEU-1, LEU1, Ly-1, Lymphocyte antigen T1/Leu-1, Lyt-1, T-cell surface glycoprotein CD5
Präsentation FITC
Reaktivität Fe
Anwendungen F
Klonalität Monoclonal
Klon f43
Wirt Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet Datenblatt ansehen
Hersteller Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datenblatt-Auszug

Anwendung Flow Cytometry: < / = 1 µg/10e6 cells. (Ref.1-2)
Background In humans, CD5 is a 55kDa T lymphocyte single chain transmembrane glycoprotein. It is present on all mature T lymphocytes, on most thymocytes and on many T cell leukemias and lymphomas. It reacts with a subpopulation of activated B cells. CD5/Lyt1 antigen is a monomeric type I transmembrane glycoprotein expressed on thymocytes, T lymphocytes, and a subset of B lymphocytes, but not on natural killer (NK) cells. It has been identified as the major ligand of the B cell antigen CD72. The frequency of CD5+ B cells exhibits strain dependent variation, and the phenotypic, anatomical, functional, developmental, and pathological characteristics of the CD5+ B cells suggest that they may represent a distinct lineage, known as B1 cells. Binding of CD5 on the T cell surface can augment alloantigen or mitogen induced lymphocyte proliferation and induces increased cytosolic free calcium, IL2 secretion, and IL2R expression. It has been proposed that CD5 negatively regulates signal transduction mediated by the T cell and B cell receptors.
Concentration 0.5 mg/ml
General Readings
  1. Ackley, C.D., and M.D. Cooper. 1992. Am. J. Vet. Res. 53:466-471.
  2. Dean, G.A., S.L. Quackenbush, C.D. Ackley, M.D. Cooper, and E.A. Hoover. 1991. Vet. Immunol. Immunopathol 28:327-335.
Storage Store the antibody undiluted at 2-8°C for one month or in (aliquots) at -20°C for longer.
This product is photosensitive and should be protected from light.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Label:
Fluorescein Isothiocyanate Isomer 1
FITC
Buffer System:
PBS containing 0.09% Sodium Azide as preservative.
State:
Liquid purified Ig fraction.
Specificity
Specificity:
Specific to Feline CD5. (Mr. 67kDa)
This antibody is useful as a pan T Cell Marker. (Ref.1)
Species:
Feline (Cat).

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