AM08141FC-N CD8 Antikörper

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0.5 mg / 500,00 €
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Kurzübersicht

Mouse anti Chicken CD8 3-298

AM08141FC-N

Produktbeschreibung für CD8

Mouse anti Chicken CD8 3-298.
Presentation: FITC
Product is tested for Flow Cytometry.

Produktdaten von CD8

Produkt-Kategorie Primärantikörper
Target-Kategorie
Menge 0.5 mg
Synonyme CD8 alpha chain, CD8A, MAL, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2
Präsentation FITC
Reaktivität Chk, Tr
Anwendungen F
Klonalität Monoclonal
Klon 3-298
Wirt Mouse
Isotype IgG2b
Shipping to Worldwide
PDF datasheet Datenblatt ansehen
Hersteller OriGene Technologies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datenblatt-Auszug

Immunogen
Swiss Prot Num:
Q0R4I4
Isotype control SM12F
Anwendung Flow Cytometry: < / = 1 µg/10e6 cells. (Ref.4)
Background The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. CD8 is expressed on most thymocytes and approximately 1/3 of peripheral blood T cells in humans. CD8 alpha/beta heterodimers are expressed only on TCR alpha/beta T cells, whereas CD8 alpha homodimers can be expressed on alpha/beta and gamma/delta T cells and some NK cells in humans. The pattern of expression in other species has not been well documented.
Concentration 0.5 mg/ml
General Readings 1. Chan, M.L., C.-L. Chen, L. Ager, and M.D. Cooper. 1988. J. Immunol. 140:2133-2138. Tu
2. Cooper, M.D., R.P. Bucy, and C.-L. Chen. 1990. In: The Avian Model in Developmental Biology: From Organism to Genes. Editions du
CNRS, pp. 239-249.
3. Tregaskes, C.A., F. Kong, E. Paramithiotis, C.-L. Chen, M.J.H. Ratcliffe, T. F. Davison, and J.R. Young. 1995. J. Immunol. 154:4485-4494.
4. Li, Z., K.E. Nestor, Y.M. Saif, Z. Fan, M. Luhtala, and O. Vainio. 1999. Poult Sci. 78:1526-1531.
Storage Store the antibody undiluted at 2-8°C for one month or in (aliquots) at -20°C for longer.
This product is photosensitive and should be protected from light.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Label:
Fluorescein Isothiocyanate Isomer 1
FITC
Buffer System:
PBS containing 0.09% Sodium Azide as preservative.
State:
Liquid purified Ig fraction.
Specificity
Specificity:
This antibody recognizes the CD8 alpha chain of both the Chicken and Turkey. (Ref.4)
Species:
Chicken and Turkey.

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