BP5074 Cytokeratin 7 Antikörper

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0.1 ml / 380,00 €
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Kurzübersicht

Guinea Pig anti Human Cytokeratin 7

BP5074

Produktbeschreibung für Cytokeratin 7

Guinea Pig anti Human Cytokeratin 7.
Presentation: Serum
Product is tested for Frozen Sections, Immunocytochemistry/Immunofluorescence, Western blot / Immunoblot, Paraffin Sections.

Produktdaten von Cytokeratin 7

Produkt-Kategorie Primärantikörper
Target-Kategorie
Menge 0.1 ml
Synonyme CK-7, CK7, K-7, K7, KRT-7, KRT7, Keratin type II cytoskeletal 7, Keratin-7, SCL, Sarcolectin
Präsentation Serum
Reaktivität Hu
Anwendungen C, ICC/IF, P, WB
Klonalität Polyclonal
Wirt Guinea Pig
Shipping to Worldwide
PDF datasheet Datenblatt ansehen
Hersteller OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datenblatt-Auszug

Immunogen
Swiss Prot Num:
P08729
Immunogen:
Synthetic peptide (C-SAGPGLLKAYSIRT) of human keratin K7 (formerly also designated cytokeratin 7), coupled to KLH.
GeneID:
3855
Anwendung Western blotting: 1/3000 (ECL).
Immunohistochemistry on frozen Sections: 1/200.
Immunohistochemistry on paraffin-embedded: 1/100
(after microwave treatment).
Cytological material.
Incubation time: 1 h at RT; extended with paraffin sections.
Positive control: Glandular epithelia (e.g. sweat glands, sebaceous glands); Merkel cells.
Background Cytokeratin 7 is a 54kD intermediate filament protein found in a variety of glandularepithelia. Cytokeratin 7 has been found in columnar and glandular epithelium of the lung, cervix, breast, bile ducts and larger collecting ducts of the kidney. It is present in the transitional epithelium of bladder as well as ovarian and lungepithelia, and occasionally staining of blood vessel cell walls, particularly endothelial cells, may be observed. However, Cytokeratin 7 is not expressed by epithelial cells of the gastrointestinal tract, colon or prostate. Keratin 7 is often co expressed with keratin 19.
General Readings Moll, R., Franke, W.W., Schiller, D.L., Geiger, B. and Krepler, R.: The catalog of human cytokeratins: Patterns of expression in normal epithelia, tumors and cultured cells. Cell 31, 11-24 (1982).
Ramaekers, F., van Niekerk C., Poels, L., Schaafsma, E., Huijsmans, A., Robben, H., Schaart, G. and Vooijs, P.: Use of monoclonal antibodies to keratin 7 in the differential diagnosis of adenocarcinomas. Am. J. Pathol. 136, 641-655 (1990)
Storage Store undiluted at 2-8°C.
DO NOT FREEZE!
Shelf life: one year from despatch.
Format
Preservatives:
0.09% Sodium Azide
Stabilizers:
0.5% BSA
State:
Stabilized antiserum
Serum
Specificity
Specificity:
Reacts with basic keratin K7 (Mr 54 000).
Excellent marker for the discrimination of specific subtypes of adenocarcinoma: e.g. adenocarcinoma of pancreas, bile duct carcinoma and transitional carcinoma of bladder are stained, whereas hepatocellular and prostate carcinomas are negative.
Detects specific subtypes of adenocarcinomas: Adenocarcinoma of pancreas, gallbladder, lung, cervix; cholangio carcinoma of liver; ductal and lobular carcinoma of breast; carcinomas of ovary; transitional cell carcinoma of bladder; mesothelioma; negative with most cases of hepatocellular carcinoma. In colorectal carcinoma early stages are reported to be negative but advanced stages of tumor development are positive for keratin K7 expression.
Species:
Human.
Gene ID 3855
FocusOn and Reviews
Bewertungen:

Accessory Products

Proteins and/or Positive Controls

Proteine zu Cytokeratin 7 (2 Produkte)

Katalog-Nr. Spezies Präs. Reinheit   Source  

Cytokeratin 7

Cytokeratin 7 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

Cytokeratin 7

Cytokeratin 7 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

Positive controls for Cytokeratin 7 (3 Produkte)

Katalog-Nr. Spezies Präs. Reinheit   Source  

Cytokeratin 7 Lysate

Western Blot: Cytokeratin 7 Lysate [NBL1-12396] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for KRT7
  Novus Biologicals Inc.

KRT7 293T Cell Transient Overexpression Lysate(Denatured)

KRT7 293T Cell Transient Overexpression Lysate(Denatured)
  Abnova Taiwan Corp.

KRT7 overexpression lysate

KRT7 overexpression lysate
0.1 mg / 295,00 €
  OriGene Technologies, Inc.
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