TA323730 Exostosin-1 Antikörper

Anti-EXT1 Rabbit Polyclonal Antibody

See related secondary antibodies

Search for all "Exostosin-1"

0.1 ml / 335,00 €
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

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Rabbit anti Human, Mouse, Rat Exostosin-1

TA323730

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  • TA323730

Produktbeschreibung für Exostosin-1

Rabbit anti Human, Mouse, Rat Exostosin-1.
Presentation: Purified
Product is tested for Western blot / Immunoblot.

Produktdaten von Exostosin-1

Produkt-Kategorie Primärantikörper
Target-Kategorie
Menge 0.1 ml
Synonyme EXT1, Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase, Multiple exostoses protein 1, Putative tumor suppressor protein EXT1
Präsentation Purified
Reaktivität Hu, Ms, Rt
Anwendungen WB
Klonalität Polyclonal
Wirt Rabbit
Isotype IgG
Shipping to Europe, USA/Canada
PDF datasheet Datenblatt ansehen
Hersteller OriGene Technologies, Inc.

Datenblatt-Auszug

Immunogen
Swiss Prot Num:
Q16394
Immunogen:
Fusion protein corresponding to C terminal 280 amino acids of human exostosin glycosyltransferase 1.
GeneID:
2131
Anwendung WB: 1:500-2000
Background Hereditary multiple exostoses (EXT) is an autosomal domint disorder characterized by the formation of cartilage-capped tumors (exostoses) that develop from the growth plate of endochondral bone. This condition can lead to skeletal abnormalities, short stature and malignt transformation of exostoses to chondrosarcomas or osteosarcomas. Linkage alyses have identified three different genes for EXT, EXT1 on 8q24.1, EXT2 on 11p11-13 and EXT3 on 19p, a family of tumor suppressor genes. Most EXT cases have been attributed to missense or frameshift mutations, which lead to loss of function of the EXT genes. EXT1 is an ER-resident type II transmembrane glycoprotein and a heparan sulphate polymerase with both D-glucuronyl and N-acetyl-D-glucosaminoglycan transferase activities. Expression of EXT1 in cells results in the alteration of the synthesis and display of cell surface heparan sulfate glycosaminoglycans. EXT1 mutations have been identified in multiple types of human tumors.
Format
Purification:
Antigen affinity purification
Buffer System:
PBS pH7.3, 0.05% NaN3, 50% glycerol.
State:
Purified

Accessory Products

Proteins and/or Positive Controls

Proteine zu Exostosin-1 (5 Produkte)

Katalog-Nr. Spezies Präs. Reinheit   Source  

Exostosin-1

Exostosin-1 Human
  Abnova Taiwan Corp.

Exostosin-1

Exostosin-1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

Exostosin-1

Exostosin-1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

Exostosin-1

Exostosin-1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Exostosin-1

Exostosin-1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Positive controls for Exostosin-1 (2 Produkte)

Katalog-Nr. Spezies Präs. Reinheit   Source  

EXT1 Lysate

Western Blot: Exostosin 1 Lysate [NBL1-10391] - Western Blot experiments.  Left-Control; Right -Over-expression Lysate for Exostosin 1.
  Novus Biologicals Inc.

EXT1 Lysate

Western Blot: Exostosin 1 Lysate [NBL1-10393] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for Exostosin 1
  Novus Biologicals Inc.
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