AP06301PU-N H/K/N-Ras Antikörper

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0.1 mg / 350,00 €
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Kurzübersicht

Rabbit anti Human, Mouse, Rat H/K/N-Ras

Produktbeschreibung für H/K/N-Ras

Rabbit anti Human, Mouse, Rat H/K/N-Ras.
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot, Paraffin Sections.

Produktdaten von H/K/N-Ras

Produkt-Kategorie Primärantikörper
Menge 0.1 mg
Präsentation Aff - Purified
Reaktivität Hu, Ms, Rt
Anwendungen P, WB
Klonalität Polyclonal
Wirt Rabbit
Molecular weight ~ 21 kDa
Shipping to Worldwide
PDF datasheet Datenblatt ansehen
Hersteller Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datenblatt-Auszug

Immunogen
Immunogen:
Synthetic peptide, corresponding to amino acids 1-50 of Human Ras.
Anwendung Western blot: 1/500-1/1000.
Immunohistochemistry on paraffin sections: 1/50-1/200.
Background The KRAS gene encodes the human cellular homolog of a transforming gene isolated from the Kirsten rat sarcoma virus. The RAS proteins are GDP/GTP-binding proteins that act as intracellular signal transducers. The most well-studied members of the RAS (derived from 'RAt Sarcoma' virus) gene family include KRAS, HRAS, and NRAS. These genes encode immunologically related proteins with a molecular mass of 21 kD and are homologs of rodent sarcoma virus genes that have transforming abilities. While these wildtype cellular proteins in humans play a vital role in normal tissue signaling, including proliferation, differentiation, and senescence, mutated genes are potent oncogenes that play a role in many human cancers.
Concentration 1.0 mg/ml
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: One year from despatch.
Format
Purification:
Affinity Chromatography using epitope-specific immunogen
Buffer System:
Phosphate buffered saline (PBS), pH7.2
Preservatives:
0.05% Sodium Azide
State:
Liquid purified Ig fraction (> 95% pure by SDS-PAGE)
Aff - Purified
Species Reactivity
Species reactivity (expected):
Mouse and Rat.
Species reactivity (tested):
Human.
Specificity
Specificity:
This antibody detects endogenous levels of RASH/RASK protein.
(region surrounding His27)

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