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NB100-122 HIF2A / HIF2 alpha Antikörper

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Rabbit anti Human, Mouse, Rat HIF2A / HIF2 alpha

NB100-122

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Produktbeschreibung für HIF2A / HIF2 alpha

Rabbit anti Human, Mouse, Rat HIF2A / HIF2 alpha.
Presentation: Purified
Product is tested for Frozen Sections, Immunoprecipitation, Western blot / Immunoblot, Paraffin Sections.

Produktdaten von HIF2A / HIF2 alpha

Produkt-Kategorie Primärantikörper
Target-Kategorie
Menge 0.1 ml
Synonyme BHLHE73, Basic-helix-loop-helix-PAS protein MOP2, Class E basic helix-loop-helix protein 73, EPAS1, Endothelial PAS domain-containing protein 1, HIF-1 alpha-like factor, HIF-2 alpha, HIF-related factor, HLF, Hypoxia-inducible factor 2 alpha, MOP2, PASD2
Präsentation Purified
Reaktivität Hu, Ms, Rt
Anwendungen C, IP, P, WB
Klonalität Polyclonal
Wirt Rabbit
Shipping to Not USA/Canada
PDF datasheet Datenblatt ansehen
Hersteller Novus Biologicals Inc.

Datenblatt-Auszug

Immunogen
Swiss Prot Num:
P97481
Immunogen:
A peptide derived from the C-terminus of mouse/human HIF-2 alpha protein.
GeneID:
13819
Add. information Research Areas: Cancer, Hypoxia
Anwendung chromatin immunoprecipitation, immunohistochemistry, Immunohistochemistry-Paraffin, immunoprecipitation, Western Blot, Used in Western blot, this antibody recognizes a band at 118kDa representing HIF-2 alpha. Also useful for immunoprecipitation and Chromatin immunoprecipitation. For more information on Immunohistochemistry, please visit the following website: http://www.ihcworld.com/_protocols/antibody_protocols/hif-2a_novus_biologicals.htm Immunohistochemical Staining Protocol, chromatin immunoprecipitation , immunohistochemistry 1:100, immunoprecipitation 5 ul/1 mg lysate, Western Blot 1:200-1:1000, Immunohistochemistry-Paraffin 1:100
Background Hypoxia contributes significantly to the pathophysiology of major categories of human disease, including myocardial and cerebral ischemia, cancer, pulmonary hypertension, congenital heart disease and chronic obstructive pulmonary disease. HIF-2 alpha is predominantly expressed in highly vascularized tissues of adult humans and endothelial cells of the embryonic and adult mouse, whereas HIF-1alpha functions primarily in extravascular tissues. HIF-2 alpha is also a potent activator of the tie-2 gene, which is known to be selectively expressed in endothelial cells.
Concentration 1.2 mg/ml
Storage Store at 4C. Do not freeze.
Format
Purification:
peptide affinity purified
Buffer System:
0.05% Sodium Azide
Purity:
peptide affinity purified
State:
Purified
Specificity
Specificity:
Specific for HIF-2 alpha/EPAS. Does not cross-react with HIF-1 alpha.
Species:
Fish, Human, Mouse, Rat
Gene ID 13819

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