TA347143 Histone H2B type 1-D Antikörper

Rabbit Polyclonal H2BK12ac Antibody

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50 µg / 392,00 €
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

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Rabbit anti Human Histone H2B type 1-D

TA347143

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Produktbeschreibung für Histone H2B type 1-D

Rabbit anti Human Histone H2B type 1-D.
Presentation: Purified
Product is tested for Enzyme Immunoassay.

Produktdaten von Histone H2B type 1-D

Produkt-Kategorie Primärantikörper
Target-Kategorie
Menge 50 µg
Synonyme H2B.1 B, H2B.b, H2B/b, H2BFB, HIRA-interacting protein 2, HIRIP2, HIST1H2BD
Präsentation Purified
Reaktivität Hu
Anwendungen E
Klonalität Polyclonal
Wirt Rabbit
Isotype IgG
Shipping to Europe, USA/Canada
PDF datasheet Datenblatt ansehen
Hersteller OriGene Technologies, Inc.

Datenblatt-Auszug

Immunogen
Swiss Prot Num:
P58876
Immunogen:
The immunogen for anti-H2BK12ac antibody: the region of histone H2B containing the acetylated lysine 12 (H2BK12ac), using a KLH-conjugated synthetic peptide.
GeneID:
3017
Anwendung ChIP/ChIP-seq (0.5-1ug/ChIP); ELISA (1:1
000); Dot blotting (1:5
000); Western blotting (1:1
000)
Background Histones are the main constituents of the protein part of chromosomes of eukaryotic cells. They are rich in the amino acids arginine and lysine and have been greatly conserved during evolution. Histones pack the D into tight masses of chromatin. Two core histones of each class H2A, H2B, H3 and H4 assemble and are wrapped by 146 base pairs of D to form one octameric nucleosome. Histone tails undergo numerous post-translatiol modifications, which either directly or indirectly alter chromatin structure to facilitate transcriptiol activation or repression or other nuclear processes. In addition to the genetic code, combitions of the different histone modifications reveal the so-called "histone code". Histone methylation and demethylation is dymically regulated by respectively histone methyl transferases and histone demethylases. Acetylation of histone H2B is associated with active genes.
Format
Purification:
Affinity purified polyclol antibody in PBS containing 0.05% azide and 0.05% ProClin 300.
State:
Purified

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