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NB500-408 HLA Class II DR + DP Antikörper

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Mouse anti Human, Porcine HLA Class II DR + DP HL-40

NB500-408

Produktbeschreibung für HLA Class II DR + DP

Mouse anti Human, Porcine HLA Class II DR + DP HL-40.
Presentation: Aff - Purified
Product is tested for Flow Cytometry, Immunoprecipitation.

Produktdaten von HLA Class II DR + DP

Produkt-Kategorie Primärantikörper
Menge 0.1 mg
Synonyme DP, HLA class II histocompatibility antigen DR, HLA-DP, HLA-DR, MHC class II antigen DR
Präsentation Aff - Purified
Reaktivität Hu, Por
Anwendungen F, IP
Klonalität Monoclonal
Klon HL-40
Wirt Mouse
Isotype IgG2a
Shipping to Not USA/Canada
PDF datasheet Datenblatt ansehen
Hersteller Novus Biologicals Inc.

Datenblatt-Auszug

Immunogen
Immunogen:
Burkitt lymphoma cell line Raji.
Add. information Research Areas: Lipid and Metabolism, Immunology
Anwendung flow cytometry / FACS analysis, immunoprecipitation, Western Blot, Optimal dilutions/concentrations should be determined by the end user., flow cytometry / FACS analysis, immunoprecipitation, Western Blot
Background The antibody is useful for detection of HLA-DR and HLA-DP positive B-cells, T-cells and monocytes in cell suspensions, in frozen sections as well as in formalin fixed paraffin embedded tissue sections. The antibody is also useful for characterization of leukemias and lymphomas. In experimental settings it can be used for selective removal of antigen carrying cells by complement mediated cytotoxicity. The antibody has excellent staining properties in histology.
General Readings This product has been used in:Momburg F et al. B-cell lymphomas of high-grade malignancy frequently lack HLA-DR, -DP and -DQ antigens and associated invariant chain. Int J Cancer 40:598-603 (1987). PubMed PMID: 3316049
Horejsi V et al. Characterization of seven new monoclonal antibodies against human DR, DR + DP and DQ1 + DQ3 antigens. Tissue Antigens 28:288-97 (1986). PubMed PMID: 2435017
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Format
Purification:
Affinity purified
Buffer System:
Sodium Azide
Purity:
Affinity purified
State:
Aff - Purified
Specificity
Specificity:
Common epitope on b-chain of human HLA-DR and HLA-DP.Also reacts with porcine MHC class II antigens (SLA-D gene products).
Species:
Human, Porcine

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