TA306314 Interleukin-23 alpha / IL23A (C-term) Antikörper

Rabbit Polyclonal IL-23 Antibody

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0.1 mg / 371,00 €
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

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Rabbit anti Human, Mouse Interleukin-23 alpha / IL23A

TA306314

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Produktbeschreibung für Interleukin-23 alpha / IL23A

Rabbit anti Human, Mouse Interleukin-23 alpha / IL23A.
Properties: (C-term)
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay, Immunocytochemistry/Immunofluorescence, Western blot / Immunoblot.

Produktdaten von Interleukin-23 alpha / IL23A

Produkt-Kategorie Primärantikörper
Target-Kategorie
Menge 0.1 mg
Synonyme IL-23 subunit alpha, IL-23p19, Interleukin-23 subunit p19, SGRF
Präsentation Aff - Purified
Reaktivität Hu, Ms
Anwendungen E, ICC/IF, WB
Klonalität Polyclonal
Wirt Rabbit
Isotype IgG
Shipping to Europe, USA/Canada
PDF datasheet Datenblatt ansehen
Hersteller OriGene Technologies, Inc.

Datenblatt-Auszug

Immunogen
Swiss Prot Num:
Q9NPF7
Immunogen:
IL-23 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human IL-23. (AP30418CP-N)
GeneID:
51561
Eigenschaften C-term
Add. information Blocking peptide available: blocking peptide (AP30418CP-N)
Anwendung ELISA.
Western BLot: 2 - 4 μg/ml.
Immunocytochemistry.
Background Like interleukin-27 (IL-27), IL-23 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the IL-12p40 subunit and a novel p19 subunit. IL-23 is secreted by activated dendritic cells, macrophages, and monocytes. Its biological activities include enhancing the proliferation of memory T cells and the production of IFN-gamma, IL-12, and TNF-alpha from activated T cells, and can stimulate macrophages to produce TNF-alpha and nitric oxide. It has also been shown to possess potent anti-tumor and anti-metastatic activity in mouse models of cancer, suggesting a potential role for IL-23 in therapeutic treatment of cancer.
General Readings
  1. Hunter CA. New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions. Nat Rev Immunol. 2005 Jul;5(7):521-31. PubMed PMID: 15999093.
  2. Oppmann B, Lesley R, Blom B, Timans JC, Xu Y, Hunte B, et al. Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12. Immunity. 2000 Nov;13(5):715-25. PubMed PMID: 11114383.
  3. Sheibanie AF, Tadmori I, Jing H, Vassiliou E, Ganea D. Prostaglandin E2 induces IL-23 production in bone marrow-derived dendritic cells. FASEB J. 2004 Aug;18(11):1318-20. Epub 2004 Jun 4. PubMed PMID: 15180965.
  4. Pirhonen J, Matikainen S, Julkunen I. Regulation of virus-induced IL-12 and IL-23 expression in human macrophages. J Immunol. 2002 Nov 15;169(10):5673-8. PubMed PMID: 12421946.
Storage Store the antibody at 2 - 8°C.
Shelf life: one year from despatch.
Format
Purification:
Affinity chromatography purified via peptide column
Buffer System:
PBS containing 0.02% sodium azide.
State:
Liquid purified Ig fraction
Aff - Purified
Specificity
Specificity:
This antibody reacts to IL-23.
Species:
Human, Mouse.

Accessory Products

Proteins and/or Positive Controls

Proteine zu Interleukin-23 alpha / IL23A (8 Produkte)

Katalog-Nr. Spezies Präs. Reinheit   Source  

Interleukin-23 alpha / IL23A

Interleukin-23 alpha / IL23A Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / 680,00 €
  OriGene Technologies, Inc.

Interleukin-23 alpha / IL23A

Interleukin-23 alpha / IL23A Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
10 µg / 139,00 €
  OriGene Technologies, Inc.

Interleukin-23 alpha / IL23A

Interleukin-23 alpha / IL23A Human > 95 %
Preparation: .
Purity Detail: >95%, as determined by Coomassie stained SDS-PAGE.
10 µg / 231,00 €
  OriGene Technologies, Inc.

Interleukin-23 alpha / IL23A

Interleukin-23 alpha / IL23A Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

Interleukin-23 alpha / IL23A

Interleukin-23 alpha / IL23A Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

Interleukin-23 alpha / IL23A

Interleukin-23 alpha / IL23A Human
  Abnova Taiwan Corp.

Interleukin-23 / IL23

Interleukin-23 / IL23 Human > 95 % pure by SDS-PAGE gel and HPLC analyses. Insect cells
  OriGene Technologies GmbH

Interleukin-23 / IL23

Interleukin-23 / IL23 Human > 95 % pure by SDS-PAGE gel and HPLC analyses. Insect cells
  OriGene Technologies GmbH

Positive controls for Interleukin-23 alpha / IL23A (3 Produkte)

Katalog-Nr. Spezies Präs. Reinheit   Source  

IL23A 293T Cell Transient Overexpression Lysate(Denatured)

IL23A 293T Cell Transient Overexpression Lysate(Denatured)
  Abnova Taiwan Corp.

IL23A overexpression lysate

IL23A overexpression lysate
0.1 mg / 295,00 €
  OriGene Technologies, Inc.

IL23 P19 Lysate

Western Blot: IL23 P19 Lysate [NBL1-11943] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for IL23A
  Novus Biologicals Inc.
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