DP3500PS LYVE-1 Antikörper

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50 µg / 280,00 €
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

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Rabbit anti Human LYVE-1

DP3500PS

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Produktbeschreibung für LYVE-1

Rabbit anti Human LYVE-1.
Presentation: Aff - Purified
Product is tested for Frozen Sections, Enzyme Immunoassay, Western blot / Immunoblot, Flow Cytometry, Paraffin Sections.

Produktdaten von LYVE-1

Produkt-Kategorie Primärantikörper
Target-Kategorie
Menge 50 µg
Synonyme CRSBP-1, CRSBP1, Cell surface retention sequence-binding protein 1, Extracellular link domain-containing protein 1, HAR, Hyaluronic acid receptor, LYVE1, Lymphatic vessel endothelial hyaluronic acid receptor 1, XLKD1
Präsentation Aff - Purified
Reaktivität Hu
Anwendungen C, E, F, P, WB
Klonalität Polyclonal
Wirt Rabbit
Shipping to Worldwide
PDF datasheet Datenblatt ansehen
Hersteller OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datenblatt-Auszug

Immunogen
Swiss Prot Num:
Q9Y5Y7
Immunogen:
Highly pure recombinant Human soluble LYVE-1 produced in insect cells (Cat.-No DA3525).
It consists of amino acid 24 (Ser) to 232 (Gly) and is fused to a C-terminal His-tag (6xHis).
GeneID:
10894
Anwendung Immunohistochemistry on Frozen and Paraffin Embedded Sections (1-5 µg/ml).
Heat mediated antigen retrieval is recommended when staining paraffin embedded sections.
Western blot (1-2 µg/ml).
ELISA (1-15 µg/ml).
Flow Cytometry (3-20 µg/ml).
Background LYVE-1 has been identified as a major receptor for HA (extracellular matrix glycosamino-glycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE-1 predicts a 322-residue type I integral membrane polypeptide 41% similar to the CD44 HA receptor with a 212-residue extracellular domain containing a single Link module the prototypic HA binding domain of the Link protein superfamily. Like CD44, the LYVE-1 molecule binds both soluble and immobilized HA. However, unlike CD44, the LYVE-1 molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels. Hence, LYVE-1 is the first lymph-specific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels.
General Readings
  1. Carriera et al., Cancer Res 61:8079, 2001.
  2. Jackson DG Trends Cardiovasc Med 13:1, 2003.
  3. Sleeman et al., Microsc Res Tech 55:61, 2001.
  4. Mäkinen et al., EMBO J 20 : 4762, 2001.
Storage Store lyophilized at 2-8°C for 6 months or at -20°C long term.
After reconstitution store the antibody undiluted at 2-8°C for one month 
or (in aliquots) at -20°C long term.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Antigen Affinity Chromatography
Buffer System:
5mM PBS, pH 7.2 without preservatives or stabilizers
State:
Lyophilized purified IgG fraction
Aff - Purified
Reconstitution:
Restore in sterile water to a concentration of 0.1-1.0 mg/ml
Species Reactivity
Species reactivity (tested):
Human.
Specificity
Specificity:
This antibody will detect LYVE-1 on the surface of lymphatic endothelial cells by Immunohistochemistry.
It detects a 70 kD LYVE-1 band in Western blotting.
This antibody is not reactive with Mouse LYVE-1.
Gene ID 10894
FocusOn and Reviews
FocusOns:

Accessory Products

Proteins and/or Positive Controls

Proteine zu LYVE-1 (10 Produkte)

Katalog-Nr. Spezies Präs. Reinheit   Source  

LYVE-1 (25-235, His-tag)

LYVE-1 Human Purified > 90 % by SDS-PAGE High-5 Insect cells
0.25 mg / 1.570,00 €
  OriGene Technologies GmbH

LYVE-1 (25-235, His-tag)

LYVE-1 Human Purified > 90 % by SDS-PAGE High-5 Insect cells
50 µg / 570,00 €
  OriGene Technologies GmbH

LYVE-1

SDS-PAGE analysis of recombinant human soluble LYVE-1 from insect cells. Sample was loaded in 10% SDS-polyacrylamide gel under reducing condition and stained with Silver stain. Human Purified > 95 % by SDS-PAGE and visualised by silver stain Insect cells
20 µg / 200,00 €
  OriGene Technologies GmbH

LYVE-1

SDS-PAGE analysis of recombinant human soluble LYVE-1 from insect cells. Sample was loaded in 10% SDS-polyacrylamide gel under reducing condition and stained with Silver stain. Human Purified > 95 % by SDS-PAGE and visualised by silver stain Insect cells
  OriGene Technologies GmbH

LYVE-1

LYVE-1 Human in vitro transl.
  Abnova Taiwan Corp.

LYVE-1

LYVE-1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

LYVE-1

LYVE-1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

LYVE-1

LYVE-1 Human
  Abnova Taiwan Corp.

LYVE-1

LYVE-1 Human
  Abnova Taiwan Corp.

LYVE-1

SDS-Page: LYVE1 Protein [NBC1-18514] - LYVE1, 24.8 kDa (229 aa), confirmed by MALDI-TOF with a purity of 90% by SDS - PAGE Protein
  Novus Biologicals Inc.

Positive controls for LYVE-1 (2 Produkte)

Katalog-Nr. Spezies Präs. Reinheit   Source  

LYVE1 Lysate

Western Blot: LYVE1 Lysate [NBL1-12770] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for LYVE1
  Novus Biologicals Inc.

XLKD1 293T Cell Transient Overexpression Lysate(Denatured)

XLKD1 293T Cell Transient Overexpression Lysate(Denatured)
  Abnova Taiwan Corp.
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