BM1262S Rabies Virus Antikörper

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0.1 mg / 310,00 €
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Kurzübersicht

Mouse anti Rabies Virus Rab-50

BM1262S

Produktbeschreibung für Rabies Virus

Mouse anti Rabies Virus Rab-50.
Presentation: Purified
Product is tested for Functional assay, Enzyme Immunoassay, Western blot / Immunoblot, Frozen Sections.

Produktdaten von Rabies Virus

Produkt-Kategorie Primärantikörper
Target-Kategorie
Menge 0.1 mg
Präsentation Purified
Anwendungen C, E, FN, WB
Klonalität Monoclonal
Klon Rab-50
Wirt Mouse
Isotype IgG2b
Shipping to Worldwide
PDF datasheet Datenblatt ansehen
Hersteller OriGene Technologies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datenblatt-Auszug

Immunogen
Immunogen:
Rabies Virus of the SAD-Vnukovo strain.
Splenocytes were fused with NS-0 cells.
Isotype control AM03110PU-N, SM12P
Anwendung

ELISA: 1/50.  
Western Blot. 
Blocking:
Rab-50 neutralizes Rabies Virus.
Immunohistochemistry on Frozen Sections. 

Background Rabies virus (Neurotropic lyssavirus) is a member of the Rhabdoviridae family. Rabies is a single stranded, neurotropic, negative sense RNA virus which encodes 5 proteins: a glycoprotein, a nucleoprotein, and three others. The mature virus has a bullet shape, a protein coat, and a lipid envelope. The outer surface of the virus is covered with thumblike glycoprotein projections 5-10 nm long and 3 nm in diameter. The virus averages approximately 780 nm in length. Virus infectivity is destroyed by lipid solvents. Rabies virus is a very successful virus, with a very wide range of hosts. It causes an acute, central nervous system infection, characterized by CNS irritation, followed by paralysis and death. Approximately 50,000 human deaths each year are caused by rabies.
Concentration 0.1 mg/ml
General Readings
  1. Máciková I, Dedek L, Vrzal V, Kontseková E, Kontsek P, Ciampor F, et al. Common and different antigenic properties of the rabies virus glycoprotein of strains SAD-Vnukovo and Pitman-Moore. Acta Virol. 1992 Dec;36(6):541-50. PubMed PMID: 1284868.
  2. Li C, Zhang F, Lin H, Wang ZC, Liu XJ, Feng ZQ, et al. Generation and characterization of the human neutralizing antibody fragment Fab091 against rabies virus. Acta Pharmacol Sin. 2011 Mar;32(3):329-37. doi: 10.1038/aps.2010.209. Epub 2011 Jan 31. PubMed PMID: 21278782.
Storage

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Format
Buffer System:
PBS
Preservatives:
0.05% Sodium Azide
State:
Liquid purified Ig fraction
Purified
Specificity
Specificity:
This Rabies Virus Antibody clone Rab-50 reacts with some specific Rabies Virus strains of vascular type from Eastern Europe.

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