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NB100-904 TP53BP1 (Cocktail) Antikörper

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Rabbit anti Human, Mouse TP53BP1

NB100-904

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  • NB100-904
  • NB100-904

Produktbeschreibung für TP53BP1

Rabbit anti Human, Mouse TP53BP1.
Properties: (Cocktail)
Presentation: Aff - Purified
Product is tested for Immunocytochemistry/Immunofluorescence, Paraffin Sections, Western blot / Immunoblot.

Produktdaten von TP53BP1

Produkt-Kategorie Primärantikörper
Target-Kategorie
Menge 0.1 ml
Synonyme 53BP1, Tumor suppressor p53-binding protein 1, p53-binding protein 1, p53BP1
Präsentation Aff - Purified
Reaktivität Hu, Ms
Anwendungen ICC/IF, P, WB
Klonalität Polyclonal
Wirt Rabbit
Shipping to Not USA/Canada
PDF datasheet Datenblatt ansehen
Hersteller Novus Biologicals Inc.

Datenblatt-Auszug

Immunogen
Swiss Prot Num:
Q12888
Immunogen:
A synthetic peptide, which represented a portion of human tumor protein p53-binding protein 1 encoded in exon 11, 12 and 19 (LocusLink ID 7158). This antibody is a cocktail hybrid of NB 100-304 and NB 100-305.
GeneID:
7158
Eigenschaften Cocktail
Add. information Research Areas: Cancer, DNA Repair
Anwendung Immunocytochemistry, Western Blot, NB 100-904 is useful for Western Blot where a band at ~220 kD is seen on SDS-PAGE. It may also be used for immunocytochemistry. Irradiated lysates demonstrate a gel shift. This antibody has not yet been tested in immunoprecipitation., Western Blot 1:1,000 - 1:10,000 (ECL), Immunocytochemistry 1:100 - 1:1,000
Background P53-binding protein 1 (53BP1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, it is phosphorylated and relocalizes to the presumptive sites of damage, specifically, double-strand breaks. This also suggests a role in DNA repair, maintaining genomic stability.
Concentration 1 mg/ml
General Readings
  1. Yanagawa T, Funasaka T, Tsutsumi S, Hu H, Watanabe H, Raz A. Regulation of phosphoglucose isomerase/autocrine motility factor activities by the poly(ADP-ribose) polymerase family-14. Cancer Res. 2007 Sep 15;67(18):8682-9. PubMed PMID: 17875708.
Storage Store at 4C. Do not freeze.
Format
Purification:
Affinity purified
Buffer System:
0.1% Sodium Azide
Purity:
Affinity purified
State:
Aff - Purified
Specificity
Specificity:
NB100-904 is specific for human 53BP1 protein.
Species:
Human, Mouse
Gene ID 7158

Accessory Products

Proteins and/or Positive Controls

Proteine zu TP53BP1 (3 Produkte)

Katalog-Nr. Spezies Präs. Reinheit   Source  

TP53BP1 (transcript variant 3)

TP53BP1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / 680,00 €
  OriGene Technologies, Inc.

TP53BP1

TP53BP1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

TP53BP1

TP53BP1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Positive controls for TP53BP1 (1 Produkte)

Katalog-Nr. Spezies Präs. Reinheit   Source  

TP53BP1 overexpression lysate

TP53BP1 overexpression lysate
  OriGene Technologies, Inc.
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