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NBP1-49288 TPMT Antikörper

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Kurzübersicht

Rabbit anti Human TPMT

Produktbeschreibung für TPMT

Rabbit anti Human TPMT.
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay, Western blot / Immunoblot.

Produktdaten von TPMT

Produkt-Kategorie Primärantikörper
Menge 0.2 mg
Synonyme anti-HGNC:12014antibody, anti-S-adenosyl-L-methionine:thiopurine S-methyltr, anti-TPMT antibody, anti-thiopurine S-methyltransferaseantibody, anti-thiopurine methyltransferase antibody
Präsentation Aff - Purified
Reaktivität Hu
Anwendungen E, WB
Klonalität Polyclonal
Wirt Rabbit
Isotype IgG
Shipping to Europe only
PDF datasheet Datenblatt ansehen
Hersteller Novus Biologicals Inc.

Datenblatt-Auszug

Immunogen
Swiss Prot Num:
Q9BS45
Immunogen:
Synthetic peptide (KLH-coupled) within residues 200-250 of human TPMT protein (Swiss Prot: P51580)
GeneID:
7172
Background This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals. A pseudogene for this locus is located on chromosome 18q.
Concentration 0.5 mg/ml
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Format
Purification:
Immunogen affinity purified
Buffer System:
PBS, pH 7.4
State:
Aff - Purified
Gene ID 7172

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