TA506222 VHL Antikörper

VHL (Von Hippel Lindau) mouse monoclonal antibody, clone OTI1E1 (formerly 1E1)

See related secondary antibodies

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0.1 ml / 379,00 €
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.



Mouse anti Human VHL OTI1E1


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Produktbeschreibung für VHL

Mouse anti Human VHL OTI1E1.
Presentation: Purified
Product is tested for Paraffin Sections, Western blot / Immunoblot.

Produktdaten von VHL

Produkt-Kategorie Primärantikörper
Menge 0.1 ml
Synonyme Protein G7, Von Hippel-Lindau disease tumor suppressor
Präsentation Purified
Reaktivität Hu
Anwendungen P, WB
Klonalität Monoclonal
Klon OTI1E1
Wirt Mouse
Isotype IgG2b
Shipping to Europe, USA/Canada
PDF datasheet Datenblatt ansehen
Hersteller OriGene Technologies, Inc.


Swiss Prot Num:
Full length human recombinant protein of human VHL(NP_000542) produced in HEK293T cell.
Isotype control AM03110PU-N, SM12P
Anwendung WB 1:4000
IHC 1:150
Background Von Hippel-Lindau syndrome (VHL) is a domintly inherited familial cancer syndrome predisposing to a variety of malignt and benign tumors. A germline mutation of this gene is the basis of familial inheritance of VHL syndrome. The protein encoded by this gene is a component of the protein complex that includes elongin B, elongin C, and cullin-2, and possesses ubiquitin ligase E3 activity. This protein is involved in the ubiquitition and degradation of hypoxia-inducible-factor (HIF), which is a transcription factor that plays a central role in the regulation of gene expression by oxygen. R polymerase II subunit POLR2G/RPB7 is also reported to be a target of this protein. Altertively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008].
Purified from mouse ascites fluids by affinity chromatography
Buffer System:
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

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