R1613CP APG7L / ATG7 Control Peptide

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50 µg / 205,00 €
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Kurzübersicht

anti APG7L / ATG7

R1613CP

Produktbeschreibung für APG7L / ATG7

anti APG7L / ATG7.
Properties: Control Peptide
Presentation: Purified

Produktdaten von APG7L / ATG7

Produkt-Kategorie Control Peptides
Target-Kategorie
Menge 50 µg
Synonyme APG7-like, Autophagy-related protein 7, Ubiquitin-activating enzyme E1-like protein
Präsentation Purified
Klonalität Polyclonal
Shipping to Worldwide
PDF datasheet Datenblatt ansehen
Hersteller OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datenblatt-Auszug

Immunogen
Swiss Prot Num:
O95352
GeneID:
10533
Anwendung Control peptide should be used at 1.0 µg per 1.0 µl of antiserum in per assay.
Background Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by Target of rapamycin (TOR) via phosphorylation of autophagy protein APG1. APG7 is a member of the autophagy family of proteins and was identified in yeast as a ubiquitin-E1-like enzyme; this function is conserved in the mammalian homolog. In mammalian cells, APG7 is essential for autophagy conjugation systems, autophagosome formation, starvation-induced bulk degradation of proteins and organelles. It has been suggested that caspase-8 may alter APG7 levels and thus the APG7 program of autophagic cell death.
Concentration 1.0 mg/ml (by weight)
Storage Store the antibody at -20°C.
Avoid repeated freezing and thawing.
Shelf life: 6 month from despatch.
Format
Purification:
Greater than 95% specific peptide
Buffer System:
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
State:
Liquid (sterile filtered)
Purified
Specificity
Specificity:
APG7L / ATG7 Control Peptide
Gene ID 10533
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