AP00056CP-N BID Control Peptide

Search for all "BID"

50 µg / 180,00 €
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Kurzübersicht

anti BID

AP00056CP-N

Produktbeschreibung für BID

anti BID.
Properties: Control Peptide
Presentation: Purified

Produktdaten von BID

Produkt-Kategorie Control Peptides
Target-Kategorie
Menge 50 µg
Synonyme BH3-interacting domain death agonist, p22 BID
Präsentation Purified
Klonalität Polyclonal
Shipping to Worldwide
PDF datasheet Datenblatt ansehen
Hersteller OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datenblatt-Auszug

Immunogen
Swiss Prot Num:
P55957
GeneID:
637
Anwendung Western blot: It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30 minutes at 37 °C.
Background Bid, a BH3 domain containing proapoptotic Bcl2 family member, is localized in the cytosolic fraction of cells as an inactive precursor. Its active form is generated upon proteolytic cleavage by caspase 8 in the Fas signaling pathway. Cleaved Bid translocates to mitochondria and releases its potent proapoptotic activity, which in turn induces cytochrome c release and mitochondrial damage. The cytochrome c releasing activity of Bid was antagonized by Bcl2. Mutation in the SH3 domain can diminish the cytochrome c releasing activity. In animal model studies, Bid deficient mice are found resistant to the lethal effects of death factor signals relayed through Fas.
Concentration 0.2 mg/ml
Storage Store the antibody undiluted at -20°C or for long term storage (in aliquots) at -70°C.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Buffer System:
PBS, pH 7.2, containing 0.1% BSA and 0.02% thimerosal
Purity:
purified
State:
Liquid peptide
Purified
Specificity
Specificity:
Control peptide for antibody AP00056PU-N only.
Gene ID 637

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