BID Control Peptide - AP00056CP-N | acris-antikoerper.de

Produktbeschreibung für BID

anti BID.
Properties: Control Peptide
Presentation: Purified

Produkt-Kategorie	Control Peptides
Menge	50 µg
Synonyme	BH3-interacting domain death agonist, p22 BID
Präsentation	Purified
Klonalität	Polyclonal
Shipping to	Worldwide
PDF datasheet	Datenblatt ansehen
Hersteller	OriGene Technologies GmbH
Material safety datasheet	MSDS for Polyclonal Antibodies (de)

Immunogen	Swiss Prot Num: P55957 GeneID: 637
Anwendung	Western blot: It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30 minutes at 37 °C.
Background	Bid, a BH3 domain containing proapoptotic Bcl2 family member, is localized in the cytosolic fraction of cells as an inactive precursor. Its active form is generated upon proteolytic cleavage by caspase 8 in the Fas signaling pathway. Cleaved Bid translocates to mitochondria and releases its potent proapoptotic activity, which in turn induces cytochrome c release and mitochondrial damage. The cytochrome c releasing activity of Bid was antagonized by Bcl2. Mutation in the SH3 domain can diminish the cytochrome c releasing activity. In animal model studies, Bid deficient mice are found resistant to the lethal effects of death factor signals relayed through Fas.
Concentration	0.2 mg/ml
Storage	Store the antibody undiluted at -20°C or for long term storage (in aliquots) at -70°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Format	Buffer System: PBS, pH 7.2, containing 0.1% BSA and 0.02% thimerosal Purity: purified State: Liquid peptide Purified
Specificity	Specificity: Control peptide for antibody AP00056PU-N only.
Gene ID	637