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AP00006CP-N Caspase-1 Control Peptide

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Kurzübersicht

anti Caspase-1

AP00006CP-N

Produktbeschreibung für Caspase-1

anti Caspase-1.
Properties: Control Peptide
Presentation: Purified

Produktdaten von Caspase-1

Produkt-Kategorie Control Peptides
Menge 50 µg
Synonyme CASP-1, CASP1, ICE, IL1BC, IL1BCE, Interleukin-1 beta convertase, Interleukin-1 beta-converting enzyme, p45
Präsentation Purified
Klonalität Polyclonal
Shipping to Worldwide
PDF datasheet Datenblatt ansehen
Hersteller OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datenblatt-Auszug

Immunogen
Swiss Prot Num:
P29466
GeneID:
834
Anwendung Western blot: It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30 minutes at 37°C.
Background Caspases are a family of cysteine proteases that are key mediators of programmed cell death or apoptosis. The precursor form of all caspases is composed of a prodomain, and large and small catalytic subunits. The active forms of caspases are generated by several stimuli including ligand-receptor interactions, growth factor deprivation and inhibitors of cellular functions. All known caspases require cleavage adjacent to aspartates to liberate one large and one small subunit, which associate into a2b2 tetramer to form the active enzyme. Caspase 1 is similar to the cell death gene CED3 of C. elegans and regulates multiple proinflammatory cytokines, including Interleukin 1b and interferon-gamma-inducing factor. Caspase 1 plays a role down stream of Caspase 8 which is involved in Fas-mediated apoptosis.
Concentration 0.2 mg/ml
Storage Upon receipt, store undiluted at -20°C or for long term storage (in aliquots) at -70°C.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Buffer System:
PBS, pH 7.2
Preservatives:
0.02% Thimerosal
Stabilizers:
0.1% BSA
State:
Liquid peptide
Purified
Specificity
Specificity:
Control Peptide for Caspase-1 Antibody Cat.-No AP00006PU-N only.
Gene ID 834

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