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AP00011CP-N Caspase-4 Control Peptide

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Kurzübersicht

anti Caspase-4

AP00011CP-N

Produktbeschreibung für Caspase-4

anti Caspase-4.
Properties: Control Peptide
Presentation: Purified

Produktdaten von Caspase-4

Produkt-Kategorie Control Peptides
Menge 50 µg
Synonyme CASP4, ICE(rel)-II, ICH2, Protease ICH-2, Protease TX
Präsentation Purified
Klonalität Polyclonal
Shipping to Worldwide
PDF datasheet Datenblatt ansehen
Hersteller OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datenblatt-Auszug

Immunogen
Swiss Prot Num:
P49662
GeneID:
837
Anwendung Western Blot: It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30 minutes at 37°C.
Background Caspase 4 is a 377 amino acid protein (43 kDa) that belongs to the Ced3/ICE family of cystein proteases. Caspase 4 is an "upstream" caspase with a long prodomain. It undergoes a cleavage upon activation, leading to p20 and p10 subunits which have 67% homology to mature Caspase 1 over the equivalent coding sequences. Caspase 4 is capable of cleaving itself and the p30 Caspase 1 precursor, and of inducing apoptosis in transfected insect or COS cells. In high concentrations, it can also cleave the nuclear DNA enzyme PARP but the biological relevance of this cleavage is unclear. Caspase 4 mRNA is found in most tissues examined with the exception of the brain. Highest expression is found in spleen and lung, with moderate expression in heart and liver. Low expression is observed with skeletal muscle, kidney, and testis.
Concentration 0.2 mg/ml
Storage Store the antibody undiluted at -20°C or for long term storage (in aliquots) at -70°C.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Buffer System:
PBS, pH 7.2, containing 0.1% BSA and 0.02% thimerosal
Purity:
purified
State:
Liquid peptide
Purified
Specificity
Specificity:
Control peptide for antibody AP00011CP-N only.
Gene ID 837

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