EA101025 17-OHP ELISA Kit

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1 kit / 255,00 €
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

EA101025

Produktdaten von 17-OHP ELISA Kit

Produkt-Kategorie ELISA Kits
Menge 1 kit
Synonyme 17-OHP
Reaktivität Hu
Shipping to Europe, USA/Canada
PDF datasheet Datenblatt ansehen
Hersteller OriGene Technologies, Inc.

Datenblatt-Auszug

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Interference:
No significant interference observed with available related molecules.
Anwendung
Specificity:
Natural and recombinant human 17-OH Progesterone
Assay Type:
Solid Phase Sandwich ELISA
Signal:
Colorimetric
Sample Type:
Cell culture supernatant, serum, plasma
Sample Volume:
25 ul
Curve Range:
0.034 – 20 ng/mL
Background The steroid 17-a-Hydroxyprogesterone (17-a-OHP) is produced by both the adrenal cortex and gonads. Even though 17-a-OHP has relatively little progestational activity, it is of intense clinical interest because it is the immediate precursor to 11-desoxycortisol (Cpd-S). Because Cpd-S is produced by 21-hydroxylation of 17-a-OHP, measurement of 17-a-OHP is a useful indirect indicator of 21-hydroxylase activity. In congenital 21-hydroxylase deficiency, the most common variety of congenital adrenal hyperplasia (CAH), 17-a-OHP is secreted in abundant excess. It is moderately elevated in the 11-ß-hydroxylase deficiency as well. Measurement of 17-a-OHP is therefore valuable in the initial diagnosis of CAH.
Assaytime 3 hours
Range 0.034 ng/ml
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