17-OHP ELISA Kit - EA101025 | acris-antikoerper.de

Produktdaten von 17-OHP ELISA Kit

Add. information	Interference: No significant interference observed with available related molecules.
Anwendung	Specificity: Natural and recombinant human 17-OH Progesterone Assay Type: Solid Phase Sandwich ELISA Signal: Colorimetric Sample Type: Cell culture supernatant, serum, plasma Sample Volume: 25 ul Curve Range: 0.034 – 20 ng/mL
Background	The steroid 17-a-Hydroxyprogesterone (17-a-OHP) is produced by both the adrenal cortex and gonads. Even though 17-a-OHP has relatively little progestational activity, it is of intense clinical interest because it is the immediate precursor to 11-desoxycortisol (Cpd-S). Because Cpd-S is produced by 21-hydroxylation of 17-a-OHP, measurement of 17-a-OHP is a useful indirect indicator of 21-hydroxylase activity. In congenital 21-hydroxylase deficiency, the most common variety of congenital adrenal hyperplasia (CAH), 17-a-OHP is secreted in abundant excess. It is moderately elevated in the 11-ß-hydroxylase deficiency as well. Measurement of 17-a-OHP is therefore valuable in the initial diagnosis of CAH.
Assaytime	3 hours
Range	0.034 ng/ml