Produktdaten von 17-OHP ELISA Kit
Produkt-Kategorie | ELISA Kits |
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Menge | 1 kit |
Synonyme | 17-OHP |
Reaktivität | Hu |
Shipping to | Europe, USA/Canada |
PDF datasheet | Datenblatt ansehen |
Hersteller | OriGene Technologies, Inc. |
Datenblatt-Auszug
Add. information |
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Anwendung |
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Background | The steroid 17-a-Hydroxyprogesterone (17-a-OHP) is produced by both the adrenal cortex and gonads. Even though 17-a-OHP has relatively little progestational activity, it is of intense clinical interest because it is the immediate precursor to 11-desoxycortisol (Cpd-S). Because Cpd-S is produced by 21-hydroxylation of 17-a-OHP, measurement of 17-a-OHP is a useful indirect indicator of 21-hydroxylase activity. In congenital 21-hydroxylase deficiency, the most common variety of congenital adrenal hyperplasia (CAH), 17-a-OHP is secreted in abundant excess. It is moderately elevated in the 11-ß-hydroxylase deficiency as well. Measurement of 17-a-OHP is therefore valuable in the initial diagnosis of CAH. |
Assaytime | 3 hours |
Range | 0.034 ng/ml |