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BB-EK0664 Mouse BAFF ELISA Kit

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Produktdaten von Mouse BAFF ELISA Kit

Produkt-Kategorie ELISA Kits
Menge 96 Tests
Reaktivität Ms
Shipping to Not USA/Canada
PDF datasheet Datenblatt ansehen
Hersteller Boster Immunoleader
Manufacturer certificates ISO 9001


Swiss Prot Num:
Add. information Sensitivity < 10 pg/ml
Anwendung Sandwich ELISA kit of Quantitative Detection for Mouse BAFF
This kit is used for quantitative detection of mouse BAFF in cell culture supernates, serum and plasma(heparin, EDTA).
There is no detectable cross-reactivity with other relevant proteins.
Background B-cell activating factor (BAFF) also known as tumor necrosis factor ligand superfamily member 13B is a protein that in humans is encoded by the TNFLSF13B gene.1,2 BAFF is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells.3All these ligands act as heterotrimers (i.e. three of the same molecule) interacting with heterotrimeric receptors4, although BAFF has been known to be active as either a hetero- or homotrimer.5 The standard used in this kit is recombinant mouse soluble BAFF (A127-L309) with molecular weight 23.2KDa.
General Readings
  1. Shu HB, Hu WH, Johnson H. TALL-1 is a novel member of the TNF family that is down-regulated by mitogens. J Leukoc Biol. 1999 May;65(5):680-3. PubMed PMID: 10331498.
  2. Schneider P, MacKay F, Steiner V, Hofmann K, Bodmer JL, Holler N, et al. BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth. J Exp Med. 1999 Jun 7;189(11):1747-56. PubMed PMID: 10359578. (Free PMC Article available, 5 images available)
  3. "Entrez Gene: tumor necrosis factor (ligand) superfamily".
  4. Oren DA, Li Y, Volovik Y, Morris TS, Dharia C, Das K, et al. Structural basis of BLyS receptor recognition. Nat Struct Biol. 2002 Apr;9(4):288-92. PubMed PMID: 11862220.
  5. Daridon C, Youinou P, Pers JO. BAFF, APRIL, TWE-PRIL: who's who? Autoimmun Rev. 2008 Feb;7(4):267-71. doi: 10.1016/j.autrev.2007.05.002. Epub 2007 Jun 21. PubMed PMID: 18295728.
Storage Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)
Range 46.9-3000 pg/ml
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