AR09102PU-N 14-3-3 protein eta (1-246, His-tag)

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0.1 mg / 320,00 €
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14-3-3 protein eta

Produktbeschreibung für 14-3-3 protein eta

14-3-3 protein eta.
Presentation: Purified

Produktdaten von 14-3-3 protein eta

Produkt-Kategorie Proteins & Growth Factors
Target-Kategorie
Menge 0.1 mg
Synonyme Protein AS1, YWHA1, YWHAH
Präsentation Purified
Molecular weight 30.3 kDa
Source E. coli
Spezies (Protein) Human
Shipping to Worldwide
PDF datasheet Datenblatt ansehen
Hersteller OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datenblatt-Auszug

Immunogen
Swiss Prot Num:
Q04917
Reinheit ≥ 95 by SDS-PAGE
Background The 14-3-3 family of proteins plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms, β, γ, ε, σ, ζ, τ and η that have been identified in mammals. The 14-3-3η (eta), a subtype of the 14-3-3 family of proteins, was found in B cells, brain, cerebrospinal fluid etc. 14-3-3η interacts with and relocalizes the A20 zinc finger protein from the insoluble to the soluble fraction, suggesting a chaperone function.
Concentration 1.0 mg/ml (By Absorbance at 280nm)
General Readings
  1. Sato S, Chiba T, Sakata E, Kato K, Mizuno Y, Hattori N, et al. 14-3-3eta is a novel regulator of parkin ubiquitin ligase. EMBO J. 2006 Jan 11;25(1):211-21. Epub 2005 Aug 11. PubMed PMID: 16096643. (Free PMC Article available, 6 images available)
  2. Chen J, Lee CT, Errico SL, Becker KG, Freed WJ. Increases in expression of 14-3-3 eta and 14-3-3 zeta transcripts during neuroprotection induced by delta9-tetrahydrocannabinol in AF5 cells. J Neurosci Res. 2007 Jun;85(8):1724-33. PubMed PMID: 17455326. (Free PMC Article available, 5 images available)
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C to -80°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Beschreibung
Description:
Recombinant Human 14-3-3η, fused to His-tag at N-terminus, was expressed in E.coli and purified by conventional chromatography techniques.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MGDREQLLQR ARLAEQAERY DDMASAMKAV TELNEPLSNE DRNLLSVAYK NVVGARRSSW RVISSIEQKT MADGNEKKLE KVKAYREKIE KELETVCNDV LSLLDKFLIK NCNDFQYESK VFYLKMKGDY YRYLAEVASG EKKNSVVEAS EAAYKEAFEI SKEQMQPTHP IRLGLALNFS VFYYEIQNAP EQACLLAKQA FDDAIAELDT LNEDSYKDST LIMQLLRDNL TLWTSDQQDE EAGEGN
Molecular weight:
(266 aa), confirmed by MALDI-TOF
Format
Buffer System:
20 mM Tris pH 8.0 containing 10% Glycerol
Purity:
≥95 by SDS-PAGE
State:
Liquid purified protein
Purified
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