AR09189PU-L 4-1BBL / TNFSF9 (71-254, His-tag)

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0.5 mg / 820,00 €
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4-1BBL / TNFSF9

AR09189PU-L

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  • AR09189PU-L

Produktbeschreibung für 4-1BBL / TNFSF9

4-1BBL / TNFSF9.
Presentation: Purified

Produktdaten von 4-1BBL / TNFSF9

Produkt-Kategorie Proteins & Growth Factors
Target-Kategorie
Menge 0.5 mg
Synonyme 4-1BB ligand, CD137L, Tumor necrosis factor ligand superfamily member 9
Präsentation Purified
Molecular weight 23.8 kDa
Source E. coli
Spezies (Protein) Human
Shipping to Worldwide
PDF datasheet Datenblatt ansehen
Hersteller OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datenblatt-Auszug

Immunogen
Swiss Prot Num:
P41273
Reinheit > 95 % by SDS - PAGE
Background 4-1BB ligand is a type 2 transmembrane glycoprotein belonging to the TNF superfamily. 4-1BBL is expressed by activated B cells, macrophages, dendritic cells, activated T cells, neurons and astrocytes. The interaction of 4-1BB with 4-1BBL strongly regulates immunity and has been proposed to preferentially control T cell responses based on studies in various murine models of cancer, infectious disease and autoimmune disease.
Concentration 1 mg/ml (determined by Bradford assay)
General Readings Lee SW., et al. (2008). Nat Immunol. 9(8):917-26.
Sharma RK., et al. (2009). Cancer Res. 69(10):4319-26.
Storage Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Beschreibung
Description:
Recombinant human 4-1BB ligand, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
AA Sequence:
MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMRE GPELSPDDPA GLLDLRQGMF AQLVAQNVLL IDGPLSWYSD PGLAGVSLTG GLSYKEDTKE LVVAKAGVYY VFFQLELRRV VAGEGSGSVS LALHLQPLRS AAGAAALALT VDLPPASSEA RNSAFGFQGR LLHLSAGQRL GVHLHTEARA RHAWQLTQGA TVLGLFRVTP EIPAGLPSPR SE
Molecular weight:
(222aa)
Format
Buffer System:
20 mM Tris-HCl buffer (pH 8.0) containing 100 mM NaCl, 20% glycerol
Purity:
>95% by SDS - PAGE
State:
Liquid purified IgG
Purified
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