AR50557PU-N ABI3 (1-366, His-tag)

Search for all "ABI3"

0.1 mg / 820,00 €
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Kurzübersicht

ABI3

Produktbeschreibung für ABI3

ABI3.
Presentation: Purified

Produktdaten von ABI3

Produkt-Kategorie Proteins & Growth Factors
Target-Kategorie
Menge 0.1 mg
Synonyme ABI gene family member 3, NESH
Präsentation Purified
Molecular weight 41.4 kDa
Source E. coli
Spezies (Protein) Human
Shipping to Worldwide
PDF datasheet Datenblatt ansehen
Hersteller OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datenblatt-Auszug

Immunogen
Swiss Prot Num:
Q9P2A4
Reinheit > 85 % by SDS - PAGE
Background ABI3, also as known as ABI gene family member 3, belongs to the ABI family. This protein is a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain, proline rich region and Src-homology 3 (SH3) domain. The Abi family members are thought to negatively regulate cell growth and transformation, including cellular transformation through v-Abl as well as mediate cell motility by regulating actin polymerization in lamellipodia and filopodia. ABI3 inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21-activated kinase.
Concentration 0.5 mg/ml (determined by Bradford assay)
General Readings Ichigotani Y., et al. (2002) Cancer Res. 62:2215-2219Miyazaki K, et al. (2000) Biochim Biophys Acta 1493 (1-2): 237–41.
Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Beschreibung
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MGSMAELQQL QEFEIPTGRE ALRGNHSALL RVADYCEDNY VQATDKRKAL EETMAFTTQA LASVAYQVGN LAGHTLRMLD LQGAALRQVE ARVSTLGQMV NMHMEKVARR EIGTLATVQR LPPGQKVIAP ENLPPLTPYC RRPLNFGCLD DIGHGIKDLS TQLSRTGTLS RKSIKAPATP ASATLGRPPR IPEPVHLPVV PDGRLSAASS ASSLASAGSA EGVGGAPTPK GQAAPPAPPL PSSLDPPPPP AAVEVFQRPP TLEELSPPPP DEELPLPLDL PPPPPLDGDE LGLPPPPPGF GPDEPSWVPA SYLEKVVTLY PYTSQKDNEL SFSEGTVICV TRRYSDGWCE GVSSEGTGFF PGNYVEPSC
Molecular weight:
(389aa)
Format
Buffer System:
20 mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 10% glycerol
Purity:
>85% by SDS - PAGE
State:
Liquid purified protein
Purified
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