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AR10585PU-L Hepatitis C Virus NS3 subtype 5a

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Hepatitis C Virus NS3 subtype 5a

AR10585PU-L

Produktbeschreibung für Hepatitis C Virus NS3 subtype 5a

Hepatitis C Virus NS3 subtype 5a.
Presentation: Purified

Produktdaten von Hepatitis C Virus NS3 subtype 5a

Produkt-Kategorie Proteins & Growth Factors
Menge 1 mg
Präsentation Purified
Source E. coli
Shipping to Worldwide
PDF datasheet Datenblatt ansehen
Hersteller Acris Antibodies GmbH
Material safety datasheet MSDS for Proteins (de)

Datenblatt-Auszug

Reinheit >95% pure as determined by 10% PAGE (coomassie staining).
Purification Method: Sepharose-Derived Purification.
Anwendung Antigen in ELISA and Western blots, excellent antigen for detection of HCV with minimal specificity problems.
Background HCV is a small 50nm, enveloped, single-stranded, positive sense RNAvirus in the family Flaviviridae.
HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase, the HCV has an exceptionally high mutation rate, a factor that may help it elude the host's immune response. Hepatitis C virus is classified into six genotypes(1-6) with several subtypes within each genotype. The preponderance and distribution of HCV genotypes varies globally. Genotype is clinically important in determining potential response to interferon-based therapy and the required duration of such therapy. Genotypes 1 and 4 are less responsive to interferon-based treatment than are the other genotypes (2, 3, 5 and 6). 
Concentration 1.0 mg/ml
Storage

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Beschreibung
Description:
The E.coli derived recombinant protein contains the full-length HCV NS3 (c33c) immunodominant region.
Specificity: Immunoreactive with sera of HCV-infected individuals, including sera with antibodies to NS3 secondary domains.
Format
Buffer System:
25mM Tris-HCl, 1mM EDTA, 1.5M Urea, 50% Glycerol
Purity:
>95% pure as determined by 10% PAGE (coomassie staining).
Purification Method: Sepharose-Derived Purification.
State:
Purified
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