AR50764PU-S IL18BP (31-194, His-tag)

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0.1 mg / 300,00 €
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Kurzübersicht

IL18BP

Produktbeschreibung für IL18BP

IL18BP.
Presentation: Purified

Produktdaten von IL18BP

Produkt-Kategorie Proteins & Growth Factors
Target-Kategorie
Menge 0.1 mg
Synonyme IL-18BP, Interleukin-18-binding protein, Tadekinig-alfa
Präsentation Purified
Molecular weight 20.0 kDa
Source E. coli
Spezies (Protein) Human
Shipping to Worldwide
PDF datasheet Datenblatt ansehen
Hersteller OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datenblatt-Auszug

Immunogen
Swiss Prot Num:
O95998
Reinheit > 90 % by SDS - PAGE
Background IL18BP functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease.
Concentration 1 mg/ml (determined by Bradford assay)
General Readings Shimizu,C., et al. (2012) Mod Rheumatol 22 (1), 73-79Fujita,T.,et al. (2011) Diabetes Res. Clin. Pract. 92 (3), E66-E69
Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Beschreibung
Description:
Recombinant human IL18BP protein, fused to His-tag at N-terminus, was expressed in E.coli.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MGSTPVSQTT TAATASVRST KDPCPSQPPV FPAAKQCPAL EVTWPEVEVP LNGTLSLSCV ACSRFPNFSI LYWLGNGSFI EHLPGRLWEG STSRERGSTG TQLCKALVLE QLTPALHSTN FSCVLVDPEQ VVQRHVVLAQ LWAGLRATLP PTQEALPSSH SSPQQQG
Molecular weight:
(187aa)
Format
Buffer System:
20 mM Tris-HCl buffer (pH 8.0) containing 0.4M UREA, 10% glycerol
Purity:
>90% by SDS - PAGE
State:
Liquid purified protein
Purified
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