AR50425PU-S XAB1 (1-374, His-tag)

Search for all "XAB1"

0.1 mg / 300,00 €
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Kurzübersicht

XAB1

Produktbeschreibung für XAB1

XAB1.
Presentation: Purified

Produktdaten von XAB1

Produkt-Kategorie Proteins & Growth Factors
Menge 0.1 mg
Synonyme ATPBD1A, GPN1, GTPase, MBDIN, NTPBP, XPA binding protein 1
Präsentation Purified
Molecular weight 44.3 kDa
Source E. coli
Spezies (Protein) Human
Shipping to Worldwide
PDF datasheet Datenblatt ansehen
Hersteller Acris Antibodies GmbH
Material safety datasheet MSDS for Proteins (de)

Datenblatt-Auszug

Immunogen
Swiss Prot Num:
Q53RZ9
Reinheit > 90 % by SDS - PAGE
Background XAB1, as known as GPN1, belongs to the GPN-loop GTPase family. Small GTPases share a biochemical mechanism and act as binary molecular switches. One important function of small GTPases in the cell is nucleocytoplasmic transport of both proteins and RNA. This protein may play a role in DNA repair and may function in activation of transcription. And it forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding protein, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation.
Concentration 1mg/ml (determined by Bradford assay)
General Readings Carre C, et al. (2011) Mol Cell Biol. 31(19):3953-62.Forget D, et al. (2010) Mol Cell Proteomics. 9(12):2827-39.
Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Beschreibung
Description:
Recombinant human XAB1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MGSHMAASAA AAELQASGGP RHPVCLLVLG MAGSGKTTFV QRLTGHLHAQ GTPPYVINLD PAVHEVPFPA NIDIRDTVKY KEVMKQYGLG PNGGIVTSLN LFATRFDQVM KFIEKAQNMS KYVLIDTPGQ IEVFTWSASG TIITEALASS FPTVVIYVMD TSRSTNPVTF MSNMLYACSI LYKTKLPFIV VMNKTDIIDH SFAVEWMQDF EAFQDALNQE TTYVSNLTRS MSLVLDEFYS SLRVVGVSAV LGTGLDELFV QVTSAAEEYE REYRPEYERL KKSLANAESQ QQREQLERLR KDMGSVALDA GTAKDSLSPV LHPSDLILTR GTLDEEDEEA DSDTDDIDHR VTEESHEEPA FQNFMQESMA QYWKRNNK
Molecular weight:
(398aa) confirmed by MALDI-TOF
Format
Buffer System:
20 mM Tris-HCl buffer, pH8.0, 10% glycerol, 1mM DTT, 50mM NaCl
Purity:
>90% by SDS - PAGE
State:
Liquid purified protein
Purified
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