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GABRA3 antibody

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Principal name

GABRA3 antibody

Alternative names for GABRA3 antibody

GABRA-3, GABA A Receptor subunit alpha-3, Gamma-aminobutyric acid receptor subunit alpha-3

SwissProt ID

P10064 (Bovin), P20236 (Rat), P26049 (Mouse), P34903 (Human)

Gene ID

2556 (GABRA3), 24947 (Gabra3), 14396

Ncbi ID

9606, NP_000799, 10116, NM_000808, NP_058765.1, NP_000799.1, NP_032093.3, NM_017069

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), Rt (Rat), African clawed frog, Bt (Bat), Chk (Chicken), Eq (Equine), Hst (Hamster), Mky (Monkey), Op (Opossum), Prim (Primate), Rb (Rabbit), Tr (Turkey), Bear, Ze (Zebrafish), GP (Guinea Pig), Por (Porcine)

Available hosts

Rabbit, Mouse, Goat

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), Frozen Sections (C)

Background of GABRA3 antibody

GABA (?-aminobutyric acid) is the primary inhibitory neurotransmitter in the central nervous system and interacts with three different receptors: GABA(A), GABA(B) and GABA(C) receptor. The ionotropic GABA(A) and GABA(C) receptors are ligand-gated ion channels that produce fast inhibitory syptic transmission. In contrast, the metabotropic GABA(B) receptor is coupled to G proteins that modulate slow inhibitory syptic transmission. Functiol GABA(B) receptors form heterodimers of GABA(B)R1 and GABA(B)R2 where GABA(B)R1 binds the ligand and GABA(B)R2 is the primary G protein contact site. Two isoforms of GABA(B)R1 have been cloned: GABA(B)R1a is a 130 kD protein and GABA(B)R1b is a 95 kD protein. G proteins subsequently inhibit adenyl cylase activity and modulate inositol phospholipid hydrolysis. GABA(B) receptors have both pre- and postsyptic inhibitions: presyptic GABA(B) receptors inhibit neurotransmitter release through suppression of high threshold calcium channels, while postsyptic GABA(B) receptors inhibit through coupled activation of inwardly rectifying potassium channels. In addition to syptic inhibition, GABA(B) receptors may also be involved in hippocampal long-term potentiation, slow wave sleep and muscle relaxation.

General readings

Chou,K.C. et al., (2004) Biochem. Biophys. Res. Commun. 316 (3), 636-642

AVARP13027_T100 - GABRA3
mouse bulbus; GABRA3 antibody - N-terminal region (AVARP13027_T100) in mouse bulbus cells using Immunohistochemistry
ARP34981_T100 - GABRA3
mouse bulbus; GABRA3 antibody - middle region (ARP34981_T100) in mouse bulbus cells using Immunohistochemistry
ARP34981_T100 - GABRA3
Human Jurkat; WB Suggested Anti-GABRA3 Antibody Titration: 2.5ug/ml. ELISA Titer: 1:312500. Positive Control: Jurkat cell lysate; GABRA3 antibody - middle region (ARP34981_T100) in Human Jurkat cells using Western Blot
PAB9678 - GABRA3
Western blot of mouse brain lysates from wild type (Control, lane 1) and Gabra3 knockout (alpha K/O, lane 2) animals showing specific immunolabeling of the ~51k Gabra3 subunit of the GABAA-R. The labeling was absent from a lysate prepared from Gabra3 knockout animals.
AP23117PU-N - GABRA3
Brain, cortex, Human: Formalin-Fixed, Paraffin-Embedded (FFPE)
TA309127 - GABRA3
Western blot of mouse brain lysates from wild type (Control) and α -knockout 3 (αK/O) animals showing specific immunolabeling of the ~51k α -subunit of the 3 GABA -R. The labeling was absent from a lysate prepared from α -knockout A3 animals.
TA323565 - GABRA3
Predicted band size: 55 kDa . Positive control: Rat brain and mouse brain tissue and C6 cells lysate. Recommended dilution: 1/ 500-1000. (Gel: 10%SDS-PAGE Lane1,2,3: Rat brain and mouse brain tissue and C6 cells lysate Lysates: 30 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute)
TA328699 - GABRA3
Western blot analysis of rat brain membranes: 1. Anti-GABA(A) a3 Receptor (extracellular) antibody, (1:200). 2. Anti-GABA(A) a3 Receptor (extracellular) antibody preincubated with the control peptide antigen.
TA328699 - GABRA3
Expression of GABA(A) a3 Receptor in rat cerebellum. Immunohistochemical staining of rat cerebellum using Anti-GABA(A) a3 Receptor (extracellular), (green), (1:100). GABA(A) a3 Receptor is localized to the molecular layer (asterisk) and a portion of the Purkinje cell body (arrows), which is outlined by axonal staining using mouse anti-neurofilament 200 (red).
TA328699 - GABRA3
Expression of GABA(A) a3 Receptor in rat insulinoma cell line. Immunocytochemical staining of intact living rat RIN-m cells using Anti- GABA(A) a3 Receptor (extracellular) antibody, (1:50) followed by goat anti-rabbit-AlexaFluor-550 secondary antibody. Extracellular staining (red) merged with live view of the cells.
TA330435 - GABRA3
mouse bulbus
TA338501 - GABRA3
Host: Rabbit; Target Name: Gabra3; Sample Tissue: Rat Kidney lysates; Antibody Dilution: 1.0 ug/ml
TA338502 - GABRA3
WB Suggested Anti-GABRA3 Antibody Titration: 2.5 ug/ml; ELISA Titer: 1:312500; Positive Control: Jurkat cell lysate
TA338502 - GABRA3
mouse bulbus
TA341213 - GABRA3
Anti-GABRA3 antibody IHC of human brain, globus pallidus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TA341214 - GABRA3
Anti-GABRA3 antibody IHC of human brain, basal nucleus of Meynert. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
CPA9289-100ul - GABRA3
Western blot analysis of GABRA3 expression in mouse brain (A); rat brain (B) whole cell lysates.
CPA9289-100ul - GABRA3
Immunohistochemical analysis of GABRA3 staining in rat brain;mouse brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.

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Primärantikörper

Katalog-Nr. Wirt Iso. Klon Präs. Reakt. Anwendungen  

GABRA3 (N-term) Antikörper
  Rabbit Anti-GABAA Receptor a 3 Antibody  
Western blot of mouse brain lysates from wild type (Control) and α -knockout 3 (αK/O) animals showing specific immunolabeling of the ~51k α -subunit of the 3 GABA -R. The labeling was absent from a lysate prepared from α -knockout A3 animals. Rabbit IgG Aff - Purified Bov, Can, Hu, Rt, Ze C, WB
0.1 ml / 383,00 €
  OriGene Technologies, Inc.

GABRA3 Antikörper
  Anti-Gabra3 Rabbit Polyclonal Antibody  
Predicted band size: 55 kDa . Positive control: Rat brain and mouse brain tissue and C6 cells lysate. Recommended dilution: 1/ 500-1000. (Gel: 10%SDS-PAGE Lane1,2,3: Rat brain and mouse brain tissue and C6 cells lysate Lysates: 30 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / 335,00 €
  OriGene Technologies, Inc.

GABRA3 Antikörper
  Rabbit Polyclonal Anti-GABA (A) alpha3 Receptor (extracellular)  
Western blot analysis of rat brain membranes: 1. Anti-GABA(A) a3 Receptor (extracellular) antibody, (1:200). 2. Anti-GABA(A) a3 Receptor (extracellular) antibody preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / 622,00 €
  OriGene Technologies, Inc.
+2 weitere Bilder

GABRA3 Antikörper
  Rabbit Polyclonal Anti-GABRA3 Antibody  
mouse bulbus Rabbit IgG Purified Ms P
0.1 mg / 360,00 €
  OriGene Technologies, Inc.

GABRA3 Antikörper
  Rabbit Polyclonal Anti-Gabra3 Antibody  
Host: Rabbit; Target Name: Gabra3; Sample Tissue: Rat Kidney lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / 360,00 €
  OriGene Technologies, Inc.

GABRA3 Antikörper
  Rabbit Polyclonal Anti-GABRA3 Antibody  
WB Suggested Anti-GABRA3 Antibody Titration: 2.5 ug/ml; ELISA Titer: 1:312500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt P, WB
0.1 mg / 360,00 €
  OriGene Technologies, Inc.
+1 weiteres Bild

GABRA3 Antikörper
  Rabbit Polyclonal Anti-GABRA3 Antibody (C-Terminus)  
Anti-GABRA3 antibody IHC of human brain, globus pallidus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Purified Hst, Hu, Ms
50 µg / 400,00 €
  OriGene Technologies, Inc.

GABRA3 Antikörper
  Rabbit Polyclonal Anti-GABRA3 Antibody (N-Terminus)  
Anti-GABRA3 antibody IHC of human brain, basal nucleus of Meynert. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Purified Hu
50 µg / 400,00 €
  OriGene Technologies, Inc.

GABRA3 (480-492) Antikörper
Brain, cortex, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) Goat Aff - Purified Bov, Bt, Elephant, Eq, Hst, Hu, Mky, Ms, Platypus, Rb, Rt P
50 µg / 380,00 €
  Acris Antibodies GmbH

CRISPR

Katalog-Nr. Spezies Donor Vector  

GABRA3 - human gene knockout kit via CRISPR
GABRA3 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / 1.290,00 €
  OriGene Technologies, Inc.

GABRA3 - human gene knockout kit via CRISPR
GABRA3 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / 1.290,00 €
  OriGene Technologies, Inc.

GABRA3 - human gene knockout kit via CRISPR
GABRA3 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / 1.290,00 €
  OriGene Technologies, Inc.

GABRA3 - human gene knockout kit via CRISPR
GABRA3 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / 1.290,00 €
  OriGene Technologies, Inc.

Gabra3 - mouse gene knockout kit via CRISPR
Gabra3 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / 1.290,00 €
  OriGene Technologies, Inc.

Gabra3 - mouse gene knockout kit via CRISPR
Gabra3 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / 1.290,00 €
  OriGene Technologies, Inc.

Gabra3 - mouse gene knockout kit via CRISPR
Gabra3 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / 1.290,00 €
  OriGene Technologies, Inc.

Gabra3 - mouse gene knockout kit via CRISPR
Gabra3 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / 1.290,00 €
  OriGene Technologies, Inc.

Lysate

Katalog-Nr.    

GABRA3 overexpression lysate
GABRA3 overexpression lysate  
0.1 mg / 295,00 €
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Katalog-Nr.    

Lenti ORF particles, GABRA3 (mGFP-tagged)-Human gamma-aminobutyric acid (GABA) A receptor, alpha 3 (GABRA3), 200 uL, >10^7 TU/mL
Lenti ORF particles, GABRA3 (mGFP-tagged)-Human gamma-aminobutyric acid (GABA) A receptor, alpha 3 (GABRA3), 200 uL, >10^7 TU/mL  
200 µl / 1.082,00 €
  OriGene Technologies, Inc.
 

Lenti ORF particles, GABRA3 (Myc-DDK-tagged)-Human gamma-aminobutyric acid (GABA) A receptor, alpha 3 (GABRA3), 200 uL, >10^7 TU/mL
Lenti ORF particles, GABRA3 (Myc-DDK-tagged)-Human gamma-aminobutyric acid (GABA) A receptor, alpha 3 (GABRA3), 200 uL, >10^7 TU/mL  
200 µl / 969,00 €
  OriGene Technologies, Inc.
 

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22 Produkte - FILTERN SIE IHR ERGEBNIS!

Verfügbare Filter

Produkttyp
  1. CRISPR (8)
  2. Human Lenti ORF Particle (2)
  3. Lysate (1)
  4. Primary Antibody (9)
  5. Rat Lenti ORF Particle (2)
Klonalität
  1. Polyclonal (9)
Target
  1. GABRA3 (9)
Eigenschaften
  1. 480-492 (1)
  2. N-term (1)
Reaktivität
  1. Human (Hu) (8)
  2. Mouse (Ms) (7)
  3. Rat (Rt) (6)
  4. Bovine (Bov) (4)
  5. Canine (Can) (3)
  6. Equine (Eq) (3)
  7. Rabbit (Rb) (3)
  8. Guinea Pig (GP) (2)
  9. Hamster (Hst) (2)
  10. Bat (Bt) (1)
  11. Elephant (1)
  12. Monkey (Mky) (1)
  13. Platypus (1)
  14. Porcine (Por) (1)
  15. Zebrafish (Ze) (1)
Anwendungen
  1. Western blot / Immunoblot (WB) (5)
  2. Paraffin Sections (P) (3)
  3. Frozen sections (C) (1)
Präsentation
  1. Purified (7)
  2. Aff - Purified (2)
Wirt
  1. Rabbit (8)
  2. Goat (1)
Bilder
  1. 1 image (9)
  2. 3+ images (1)
Images: Applications
  1. IHC (5)
  2. Western blot / Immunoblot (WB) (5)
  3. Immunofluorescence (IF) (1)
  4. Paraffin Sections (P) (1)
Spezies (CRISPR)
  1. Human (4)
  2. Mouse (4)
Donor Vector
  1. GFP-Puro (2)
  2. Luciferase-Puro (2)
  3. RFP-BSD (2)
  4. mBFP-Neo (2)
Hersteller
  1. Acris - OriGene (22)
Service
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