PQBP1 antibody

Principal name

PQBP1 antibody

Alternative names for PQBP1 antibody

Polyglutamine-binding protein 1, PQBP-1, NPW38, 38 kDa nuclear protein containing a WW domain, Polyglutamine tract-binding protein 1

SwissProt ID

O60828 (Human), Q2HJC9 (Bovin), Q4VY36 (Human), Q6PCT5 (Rat), Q91VJ5 (Mouse)

Gene ID

10084 (PQBP1), 54633 (Pqbp1), 302557

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of PQBP1 antibody

PQBP1 may suppress the ability of POU3F2 to transactivate the DRD1 gene in a POU3F2 dependent manner. It can activate transcription directly or via association with the transcription machinery. PQBP1 may be involved in ATXN1 mutant-induced cell death. The interaction with ATXN1 mutant reduces levels of phosphorylated RNA polymerase II large subunit.
Defects in PQBP1 are the cause of Renpenning syndrome 1 (RENS1); also known as Sutherland-Haan X-linked mental retardation syndrome (SHS) or X-linked mental retardation syndromes MRXS3/MRXS8/MRX55. The clinical features are mental retardation, microcephaly, short stature, and small testes. The craniofacies tends to be narrow and tall with upslanting palpebral fissures, abnormal nasal configuration, cupped ears, and short philtrum. The nose may appear long or bulbous, with overhanging columella. Less consistent manifestations include ocular colobomas, cardiac malformations, cleft palate, and anal anomalies. RENS1 is more frequently in males than in females where little or no expression is found.

General readings

Waragai M., et al. (1999) Hum Mol Genet. 8:977-987.Waragai M C., et al. (2000) Biochem Biophys Res. 273: 592-595.

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Primärantikörper

Katalog-Nr. Wirt Iso. Klon Präs. Reakt. Anwendungen  

PQBP1 Antikörper

  Rabbit Polyclonal anti-PQBP1 antibody  
WB Suggested Anti-PQBP1 Antibody Titration: 2.5ug/ml; ELISA Titer: 1:312500; Positive Control: Human Lung Rabbit IgG Purified Hu P, WB
0.1 mg / 325,00 €
  OriGene Technologies, Inc.

PQBP1 Antikörper

  Rabbit Polyclonal Anti-PQBP1 Antibody  
WB Suggested Anti-PQBP1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: OVCAR-3 cell lysate Rabbit IgG Purified Hu WB
50 µg / 325,00 €
  OriGene Technologies, Inc.

CRISPR

Katalog-Nr. Spezies Donor Vector  

PQBP1 - human gene knockout kit via CRISPR

PQBP1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / 1.200,00 €
  OriGene Technologies, Inc.

PQBP1 - human gene knockout kit via CRISPR

PQBP1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / 1.290,00 €
  OriGene Technologies, Inc.

PQBP1 - human gene knockout kit via CRISPR

PQBP1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / 1.290,00 €
  OriGene Technologies, Inc.

PQBP1 - human gene knockout kit via CRISPR

PQBP1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / 1.290,00 €
  OriGene Technologies, Inc.

Pqbp1 - mouse gene knockout kit via CRISPR

Pqbp1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / 1.290,00 €
  OriGene Technologies, Inc.

Pqbp1 - mouse gene knockout kit via CRISPR

Pqbp1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / 1.290,00 €
  OriGene Technologies, Inc.

Proteins & Growth Factors

Katalog-Nr. Spezies Präs. Reinheit Source  

PQBP1 (transcript variant 2)

  Purified recombinant protein of Homo sapiens polyglutamine binding protein 1 (PQBP1), transcript variant 2  
PQBP1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / 680,00 €
  OriGene Technologies, Inc.

PQBP1 (transcript variant 5)

  Purified recombinant protein of Homo sapiens polyglutamine binding protein 1 (PQBP1), transcript variant 5  
PQBP1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / 680,00 €
  OriGene Technologies, Inc.

PQBP1 (transcript variant 1)

  Recombinant protein of human polyglutamine binding protein 1 (PQBP1), transcript variant 1  
PQBP1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regulärer Preis: 20 µg / 680,00 €

Sonderpreis: 20 µg / 398,00 €

  OriGene Technologies, Inc.

PQBP1 (transcript variant 3)

  Purified recombinant protein of Homo sapiens polyglutamine binding protein 1 (PQBP1), transcript variant 3  
PQBP1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / 680,00 €
  OriGene Technologies, Inc.

PQBP1 (transcript variant 4)

  Purified recombinant protein of Homo sapiens polyglutamine binding protein 1 (PQBP1), transcript variant 4  
PQBP1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / 680,00 €
  OriGene Technologies, Inc.

PQBP1 (transcript variant 10)

  Purified recombinant protein of Homo sapiens polyglutamine binding protein 1 (PQBP1), transcript variant 10.  
PQBP1 Human > 80 %
Preparation: or Add: Recombint proteins was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / 680,00 €
  OriGene Technologies, Inc.

PQBP1 (1-265, His-tag)

PQBP1 Human Purified > 95 % by SDS - PAGE E. coli
0.5 mg / 730,00 €
  Acris Antibodies GmbH

PQBP1 (1-265, His-tag)

PQBP1 Human Purified > 95 % by SDS - PAGE E. coli
0.1 mg / 300,00 €
  Acris Antibodies GmbH

Lysate

Katalog-Nr.    

PQBP1 overexpression lysate

PQBP1 overexpression lysate  
0.1 mg / 280,00 €
  OriGene Technologies, Inc.

PQBP1 overexpression lysate

PQBP1 overexpression lysate  
0.1 mg / 280,00 €
  OriGene Technologies, Inc.

PQBP1 overexpression lysate

PQBP1 overexpression lysate  
0.1 mg / 280,00 €
  OriGene Technologies, Inc.

PQBP1 overexpression lysate

PQBP1 overexpression lysate  
0.1 mg / 280,00 €
  OriGene Technologies, Inc.

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