WT1 / Wilms tumor protein antibody

Principal name

WT1 / Wilms tumor protein antibody

Alternative names for WT1 / Wilms tumor protein antibody

WT33

SwissProt ID

O62651 (Pig), P19544 (Human)

Gene ID

7490 (WT1)

Available reactivities

Hu (Human), Can (Canine), Ms (Mouse), Por (Porcine), Rb (Rabbit), Rt (Rat), Chk (Chicken), Ze (Zebrafish), African clawed frog, Bov (Bovine), Eq (Equine)

Available hosts

Mouse, Rabbit, Goat

Available applications

Paraffin Sections (P), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF), ELISA (detection) (E(detection)), Frozen Sections (C)

Selected product citations ‐ of AP15857PU-M

1. Yates LL, Papakrivopoulou J, Long DA, Goggolidou P, Connolly JO, Woolf AS, et al. The planar cell polarity gene Vangl2 is required for mammalian kidney-branching morphogenesis and glomerular maturation. Hum Mol Genet. 2010 Dec 1;19(23):4663-76. doi: 10.1093/hmg/ddq397. Epub 2010 Sep 14. PubMed PMID: 20843830. 
2. Vasilopoulou, E;Kolatsi-Joannou, M;Lindenmeyer, MT;White, KE;Robson, MG;Cohen, CD;Sebire, NJ;Riley, PR;Winyard, PJ;Long, DA;2016Loss of endogenous thymosin β4 accelerates glomerular disease. Kidney Int. PubMed PMID: 27575556

Background of WT1 / Wilms tumor protein antibody

WT1 is a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilm\'s tumors. Multiple transcript variants, resulting from alternative splicing at two coding exons, have been well characterized. There is also evidence for the use of non-AUG (CUG) translation initiation site upstream of, and in-frame with the first AUG, leading to additional isoforms.This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilm\'s tumors. Multiple transcript variants, resulting from alternative splicing at two coding exons, have been well characterized. There is also evidence for the use of non-AUG (CUG) translation initiation site upstream of, and in-frame with the first AUG, leading to additional isoforms. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated.

General readings

Ruteshouser,E.C., (2008) Genes Chromosomes Cancer 47 (6), 461-470

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Primärantikörper

Katalog-Nr. Wirt Iso. Klon Präs. Reakt. Anwendungen  

WT1 / Wilms tumor protein Antikörper

  WT1 Rabbit Polyclonal Antibody  
Western blot analysis of kidney cell lysate using WT1 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / 335,00 €
  OriGene Technologies, Inc.

WT1 / Wilms tumor protein Antikörper

  Mouse Monoclonal Antibody against Wilms Tumor 1 (6F-H2)  
Western Blot- Wilms Tumor 1 Antibody (6F-H2) detects WT1 in 293 cell lysate Mouse IgG1 6F-H2 Purified Hu P, WB
0.1 ml / 450,00 €
  OriGene Technologies, Inc.

WT1 / Wilms tumor protein Antikörper

  Rabbit polyclonal antibody to WT1 (Wilms tumor 1)  
Wilms Tumor 1 antibody detects Wilms Tumor 1 protein at nucleus and cytosol on mouse testis by immunohistochemical analysis. Sample: Paraffin-embedded mouse testis. Wilms Tumor 1 antibody (TA308577) dilution: 1:500. Rabbit IgG Aff - Purified Hu, Rt ICC/IF, P, WB
0.1 ml / 415,00 €
  OriGene Technologies, Inc.

WT1 / Wilms tumor protein Antikörper

  Mouse Monoclonal WT1 Antibody  
Immunohistochemistry staining of Paraffin Mesothelioma tissue by WT1 antibody (dilution: 1:100 - 1:500; visualization of staining: Nuclear) Mouse IgG1 6F-H2 Purified Hu P
1 ml / 455,00 €
  OriGene Technologies, Inc.

WT1 / Wilms tumor protein Antikörper

  Rabbit Polyclonal Anti-WT1 Antibody  
WB Suggested Anti-WT1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: HT1080 cell lysate Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Por, Rb, Rt P, WB
0.1 ml / 360,00 €
  OriGene Technologies, Inc.

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